Specifically, a marked SF3B1 overexpression was found in GBM compared to non-tumor brain tissues (control-tissues) in our cohort (n = 22 and 4, respectively; Fig. 1d; Fig. S2f), which was also corroborated in another well-characterized external patient cohort (Rembrandt; n = 219 and 28, respectively; Fig. 1d; Fig. S2g). This evidence concerns the gene SF3B1 and neoplasm.