This idea is further supported by the fact that SRSF1 and SF3B1 are functionally connected since SRSF1 directly interacts with the U2-snRNP complex where SF3B1 takes part [15], and by our data indicating that SRSF1 expression is strongly correlated with SF3B1, MTOR, and CCTNB1 expression in GBM. Here, SF3B1 is linked to glioblastoma.