BCL2L1 and neoplasm: More specifically, BCL2L1 has nine SVs, and two of them, Bcl-xL and Bcl-xS, are commonly reported to be associated with cancer [6, 10], being Bcl-xL an anti-apoptotic and oncogenic, while Bcl-xS acts as a pro-apoptotic tumor suppressor (Fig. 9g).