TLR2 and autism: The top gene ontology functions enriched in the genes associated with these risk SNPs at P-value threshold of 5 × 10–4 in the external autism GWAS (Additional file 1: Table S3) are also pyrimidine ribonucleotide metabolic process (GO:0009218), toll-like receptor 2 signaling pathway (GO:0034134) and protein localization to axon (GO:0099612).