IDH1 and central nervous system cancer: Further research quantified the prognostic value of PLR, NLR, and LMR based on the IDH mutation status in glioma and noted that a low NLR was associated with a better prognosis in the IDH-wild glioblastoma group, while PLR was predictive of survival in patients with primary glioblastoma and the IDH-wild GBM group [11].