CXCL8 and infection: However, when acetate was included in the Hi2019WT infection assay, an anti-inflammatory effect was observed that resulted in a 47% (2-Way ANOVA, p = 0.0021) and 26% (2-Way ANOVA, p = 0.0001) reduction of IL-6 and IL-8 expression, while IL-1β expression was essentially unchanged.