This is relevant for tumor entities where specific fusion partners determine the diagnosis, like soft tissue sarcomas; for example, EWSR1-FLI1 is indicative for Ewing sarcoma, EWSR1-ATF1 for clear cell sarcoma, and EWSR1-DDIT3 for myxoid liposarcoma. This evidence concerns the gene FLI1 and Ewing sarcoma.