One is the benign adult familial myoclonic epilepsy (BAFME), caused by the abnormal expansion of (TTTCA)n and (TTTTA)n in intron 4 of sterile α-motif domain-containing 12 (SAMD12), in which SAMD12 protein is significantly lowered in patients’ brain (occipital lobe) [31]. This evidence concerns the gene SAMD12 and epilepsy, familial adult myoclonic.