In CHF mice injected with agomir‐miR‐30a‐5p adenovirus vectors, EF%, FS, LV+dP/dtmax and LV‐dP/dtmax levels were reduced, while LVIDd, LVIDs and LVEDP levels were augmented (Figure 4C–F); the contents of BNP, CTn‐I and Ang II were amplified; SOD activity was decreased while MDA content was increased; the levels of TNF‐α, IL‐1β and IL‐6 were also elevated (Figure 4G–K). This evidence concerns the gene NPPB and congestive heart failure.