BCL2 and congestive heart failure: Through the histopathological observation and apoptosis detection, it was validated that the upregulation of HOTAIR in CHF mice could improve the abnormal fiber arrangement and mitigate inflammatory cell infiltration but decrease CVF and apoptosis rate induced by CHF (Figure 2L‐N), while caspase‐3 and Bax contents were decreased but Bcl‐2 level was enriched (Figure 2O).