The outcome of ELISA implied that the contents of HF markers such as BNP, CTn‐I and Ang II were elevated; the SOD activity was impaired, while MDA content was increased; the levels of inflammatory factor TNF‐α, IL‐1β and IL‐6 were also elevated in CHF mice (Figure 1E–I). The gene discussed is IL1B; the disease is hydrops fetalis.