Further study demonstrated important enriched cancer-associated pathways related to the dysregulated miRNAs, including endometrial cancer, the p53 signaling pathway, non-small cell lung cancer, small cell lung cancer, transcriptional dysregulation in cancer, basal cell carcinoma, acute myeloid leukemia, renal cell carcinoma, colorectal cancer, choline metabolism in cancer, melanoma, pancreatic cancer, prostate cancer, the Ras signaling pathway, glioma, pathways in cancer, and proteoglycans in cancer (Fig. 2). Here, TP53 is linked to renal cell carcinoma.