TP53 and Familial prostate cancer: Interestingly, there were 17 cancer-associated pathways enriched into the dysregulated 18 miRNAs, including endometrial cancer, p53 signaling pathway, non-small cell lung cancer, small cell lung cancer, transcriptional misregulation in cancer, basal cell carcinoma, acute myeloid leukemia, renal cell carcinoma, colorectal cancer, choline metabolism in cancer, melanoma, pancreatic cancer, prostate cancer, Ras signaling pathway, glioma, pathways in cancer, and proteoglycans in cancer (p < 0.02; Fig. 2).