Carriageof rs10902158 GG and rs7111432 AA in introns of PKP3and TMEM16J, respectively, acts additively with a vitamin Ddeficiency and “pathogenic” genotypes of rs5743708 (TLR2)and rs8177374 (TIRAP) on tuberculosis predisposition (Horneet al., 2012; Gupta et al., 2016). The gene discussed is TLR2; the disease is tuberculosis.