Another study showed that eight-week Lactobacillus gasseri A5 supplementation in asthmatic children improved lung function, reduced asthma symptom scores, and increased asthma control test (ACT) score significantly diminishing the production of TNF-α, IFN-γ, IL-12, and IL-13 by peripheral blood mononuclear cells [26]. This evidence concerns the gene IL13 and asthma.