Although phenoscanner database (http://www.phenoscanner.medschl.cam.ac.uk/) indicated that rs2104286 had an eQTL effect on IL2RA in esophagus gastroesophageal junction and heart atrial appendage (from GTEx.v7) and rs12251307 had an eQTL effect on IL2RA in whole blood (from BIOSQTL), they are not associated with CD25 expression in CD19+ B cells in either healthy controls or T1D individuals (all P > 0.05), as shown in Figures 2(c) and 2(d). The gene discussed is CD19; the disease is type 1 diabetes mellitus.