Nevertheless, patients with coronavirus disease 2019 (COVID-19) present with gastrointestinal symptoms, given that angiotensin-converting enzyme 2 (ACE2), which SARS-CoV-2 uses as a host cell entry receptor (144), is ubiquitously present in the human gut, including small intestine and colonic enterocytes, hepatocytes and cholangiocytes. Here, ACE2 is linked to COVID-19.