PDLIM7 and neoplasm: Furthermore, EBV-associated LMP1, LMP2, EBER, EBNA, and BART play important roles in the differentiation, proliferation, and apoptosis of tumor cells, suggesting that EBV is involved in the pathogenesis of GBM, although the mechanisms remain elusive (Zavala-Vega et al., 2019; Strojnik et al., 2017).