MOG and Epstein-Barr virus infection: One study found cross-reactivity between EBNA-1 and myelin oligodendrocyte glycoprotein (MOG), in which EBV infection triggered the production of anti-MOG antibodies thereby elevating MOG concentrations and inducing the development of ADEM (Selter et al., 2010; Lalive et al., 2011; Nakamura et al., 2017).