Although circulating 18:1n-9 might partially reflect dietary intake of MUFA-rich sources (e.g., olive oil or rapeseed oil) (32, 33), 18:1n-9 in plasma is primarily endogenously synthesized from SFA by SCD-1 and has been associated with the incidence of type-2 diabetes in a pooled sample of 17 prospective studies and with elevated liver enzymes in one cross-sectional study (34, 35). Here, SCD is linked to type 2 diabetes mellitus.