Compared to patients with a focus score of FLS <1 or NSCS/SCS, a focus score ≥1 is more strongly associated with the main phenotypic features of SS, including positive anti-SSA/SSB and rheumatoid factor, high ANA titers and immunoglobulin (Ig)G concentration, presence of an ocular staining score ≥3, and unstimulated whole salivary flow rates <0.1 ml/min (32). This evidence concerns the gene SSB and synovial sarcoma.