In comparison to their respective control: hAEC- Reduced A6+ and Pan-CK+ Liver progenitor cells (LPC) by twofold and threefold, respectively. hAEC-CM:- Reduced ALT, (2.4 folds) and AST, (3.6 folds)- Reduced the number of α-SMA+ cells. Both treatments:- Reduced liver fibrosis area. The gene discussed is ACTA1; the disease is Hepatic fibrosis.