EGFR and infection: We also showed that HAdV serotypes associated with severe and occasionally fatal infections (e.g., HAdV-E4 and HAdV-B7) provoke a sustained pro-inflammatory EGFR/NF-κB/IL-8 response compared to HAdV-C2/5 (Horwitz, 1995; Zeng and Carlin, 2019).