Supplementary Figures S1C, D demonstrate the expression of LINC00883 in glioma and normal samples in the GSE4290 dataset and TCGA database. The starBase website (http://starbase.sysu.edu.cn/index.php) predicted that LINC00883 and NEK1 were positively correlated (Supplementary Figure S1E), and that NEK1 expression was also significantly higher in glioma samples than that in the normal samples (Supplementary Figure S1F). The RNA22 website further predicted the presence of binding sites between LINC00883 and miR-136 (Figure 1A) as well as between NEK1 and miR-136 (Figure 1B). Here, DUBR is linked to central nervous system cancer.