NTRK1 and hepatocellular carcinoma: Lenvatinib (LEN), a new inhibitor of multiple receptor tyrosine kinases by oral administration, such as vascular endothelial growth factor (VEGF) receptors one to three, fibroblast growth factor (FGF) receptors one to four, platelet-derived growth factor (PDGF) receptor α, RET, and KIT, was approved as a preferred drug for the therapy of HCC with better antitumor efficacy than SOR (Kudo et al., 2018; Zhao et al., 2020).