Sadava et al. (2002) found that the combination of TFR and artemisinin could reduce small cell lung cancer drug resistance. The low molar concentration of artemisinin after pretreatment could kill the cells in SCLC. Upadhyay et al. (2019) found that thymoquinone-NP modified transferrin successfully couples two distinct miRNA pathways, enhances the apoptosis and death cascade of extremely lethal NSCLC cells, and limits these migration cells without producing any significant toxicity like the widely used combination of chemotherapeutic drugs. Here, TFRC is linked to small cell lung carcinoma.