Emerging evidence suggests a link between AD and oral health, based on self-reported oral health-related quality of life (OHRQoL), objective indicators of oral health clinical assessments (e.g., missing teeth and gingival bleeding) (Ericsson et al., 2009; Zuluaga et al., 2012), and other indicators, including oral microbiota (Sureda et al., 2020), active potent neuroinflammatory regulators (e.g., IL-1β, IL-6, and TNF-α) (El Idrissi et al., 2021), and high salivary cortisol levels (Venturelli et al., 2016). Here, TNF is linked to Alzheimer disease.