Interestingly, correction based on specific fiber type markers indicated a positive correlation between DUX4 signature expression and regenerating myofibers (i.e. MYH3 and to a lesser extent MYH8), corresponding with the described increased signs of muscle regeneration in FSHD-affected muscle (Supplemental Fig. S7)44. The gene discussed is MYH8; the disease is facioscapulohumeral muscular dystrophy.