SC-Caller [66] identified 598 SNVs distributed over the genome portion not affected by CNVs, including several variants detected in the original study (e.g., LINGO2, IL7R, MYH11, FUS, PTPRD, LRP1B, TSHZ3), as well as other mutations affecting essential driver genes in CRC (e.g., APC, TP53, NRAS). Here, PTPRD is linked to colorectal carcinoma.