It has been reported that NFAT1 is highly expressed and aberrantly activated in various human cancers, including breast cancer [45], pancreatic cancer [46], lung cancer [47], cervical cancer [48], and colon cancer [49], as well as melanoma [17], and contributes to the initiation, progression, and metastasis of these diseases. The gene discussed is NFATC2; the disease is familial pancreatic carcinoma.