The purity of cancer-derived transcripts of PAAD or KIRC was markedly lower than that of EWS, GIST, and GBM (q< 0.05; Mann-Whitney U test; Benjamini-Hochberg, BH, adjusted), suggesting that the PAAD or KIRC were stromal component-rich tumors (Figure 2B). Here, EWSR1 is linked to gastrointestinal stromal tumor.