Of note, for patients who have an increased risk of HAE attacks associated with known triggers (e.g., invasive dental, medical, or surgical procedures and/or stressful life events), short‐term prophylaxis (STP) with a single dose of C1INH (1–12 h prior to the stressor) or a short course of anabolic steroids (started 5–7 days before the event and continued for 2–5 days after) may be appropriate13; however, the current review is focused on LTP. This evidence concerns the gene SERPING1 and hereditary angioedema.