Of the two labelled as likely deleterious, one was the rs13107325 variant within the metal cation symporter SLC39A8 transcript, being previously associated with a wide-range of traits including inferior posterior and flocculonodular lobule [44], striatum and putamen volumes [44, 45], schizophrenia [33, 45], neurodevelopmental outcomes and intelligence test performance [46, 47] and numerous other factors [44, 48–50] (http://www.nealelab.is/uk-biobank/). This evidence concerns the gene SLC39A8 and schizophrenia.