Another example of a pleiotropic locus is a 46 kb window (chr 19, 49,206,108–49,252,151), harboring variants adjacent to or within FUT2 that are associated with diverse traits (Fig. 4b and Supplementary Data 10), including immune (Crohn’s disease and type 1 diabetes), anthropometric (waist-to-hip ratio and offspring birth weight), cardiometabolic (blood pressure, LDL, and total cholesterol) and renal (BUN and UACR). Here, FUT2 is linked to Crohn disease.