Maroteaux–Lamy syndrome, also known as MPS VI, is due to the deficiency of the enzyme N-acetylgalactosamine 4-sulfatase (arylsulfatase B) [1, 2], which leads to the accumulation of glycosaminoglycans (GAGs) throughout the body, particularly dermatan sulfate. The gene discussed is ARSB; the disease is mucopolysaccharidosis type 6.