CYP3A4 and hepatocellular carcinoma: When we merged these hub genes with differentially expressed genes in GSE14520 dataset and differentially expressed genes of hepatocellular carcinoma in GEPIA database, seven communal genes were found, they were AURKA, CDK1, CCNB1, TOP2A, CYP3A4, CYP2C9, and CYP2B6 (Fig. 3B).