Besides, AURKA, CCNB1, CDK1 and TOP2A positively and significantly correlated with poor prognosis of hepatocellular carcinoma, while CYP2C9 and CYP3A4 negatively and significantly correlated with poor prognosis of hepatocellular carcinoma, but there was not significant correlation between the expression of CYP2B6 and prognosis of hepatocellular carcinoma (Fig. 4H-N). Here, TOP2A is linked to hepatocellular carcinoma.