When we merged these hub genes with differentially expressed genes in GSE14520 dataset and differentially expressed genes of hepatocellular carcinoma in GEPIA database, seven communal genes were found, they were AURKA, CDK1, CCNB1, TOP2A, CYP3A4, CYP2C9, and CYP2B6 (Fig. 3B). This evidence concerns the gene CYP2B6 and hepatocellular carcinoma.