Univariate Cox regression analysis revealed that among the five clock genes, TIMELESS (P = 0.034, HR = 1.19 [1.09, 1.32]) and RORA (P = 0.042, HR = 0.88 [0.78, 0.99]) were correlated greatly with the OS of NSCLC (Fig. 3A). The gene discussed is CLOCK; the disease is non-small cell lung carcinoma.