ADGRE1 and pulmonary fibrosis: C1qa, Fcgr1, C1qb, C1qc, Ccr5, Slc11a1, Aif1, Emr1 and Cxcl10 were identified as the most closely connected module which were highlighted in yellow, including 9 nodes and 32 edges (Fig. 2F), and the genes in this region were upregulated in pulmonary fibrosis.