Six cytokines (IL2, IL4, IL10, IFNγ, TNF, TGFβ) and two mediators (FOXP3 or scurfin [master gene controlling the development and function of regulatory cells], CTLA4 [antigen-4 associated with cytotoxic T-lymphocyte; it is a molecule that inhibits activation of T lymphocytes]) were evaluated in the placenta and, except for IL2, showed a significant difference between the infection and non-infection states, with higher levels when in the presence of infection; Except for TNF, the others showed no difference by Plasmodium species. This evidence concerns the gene TNF and infection.