TNFAIP3 and inflammatory bowel disease: To determine whether these inflammatory pathways could contribute to intestinal injury in patients with IBD, we measured A20 and ABIN-1 mRNA and protein levels in colonic mucosal biopsies from non-IBD and IBD patients, stratifying the IBD samples by whether they were obtained from endoscopically inflamed or noninflamed areas (Supplemental Table 1).