In addition, the main signaling pathways were identified by KEGG enrichment analysis, revealing that the over-expressed genes were primarily involved in the PI3K-Akt signaling pathway (hsa04151), focal adhesion (hsa04510), dilated cardiomyopathy (hsa05414), and small cell lung cancer (hsa05222, Figure 8 and Supplementary Table 5B). The gene discussed is AKT1; the disease is small cell lung carcinoma.