Our estimates better refined the previously reported RRs of 2-7 for BRCA1 carriers3,6,8 and approximately 2.6 for BRCA2 carriers (Data Supplement).2,8 Notably, our findings showed that the stomach cancer RR for female BRCA2 carriers was higher than the estimate for male carriers although this translated in similar absolute risks, given the higher incidence of male stomach cancer in the general population. Here, BRCA1 is linked to gastric neoplasm.