Briefly, miR-19a/b-3p, miR-25-3p, miR-22-3p, miR-210-3p, miR-93-5p, and miR-199a-3p, present at high levels in the blood of TNBC patients, regulate several cancer-related pathways, as PI3K/Akt/mTOR, HIF-1, TNF, FoxO, Wnt, and JAK/STAT, PD-1/PD-L1 and EGFR tyrosine kinase inhibitor resistance (TKIs) [76]. The gene discussed is HIF1A; the disease is cancer.