However, PRAME expression was not found in any of the CTCL lymphoma subtypes assessed in this study, including both indolent (MF, CD30+ lymphoproliferative disorder, primary cutaneous anaplastic large T-cell lymphoma, primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder, and subcutaneous panniculitis-like T-cell lymphoma) as well as aggressive (leukemic MF, Sezary Syndrome, and angiocentric T-cell lymphoma) subtypes. This evidence concerns the gene CD4 and Sezary syndrome.