The sample included 25 cases of mycosis fungoides (53.2%), 2 of Sezary Syndrome (4.3%), 5 of CD30+ lymphoproliferative disorder (10.6%), 7 of primary cutaneous anaplastic large T-cell lymphoma (14.9%), 3 of primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (6.4%), 4 of angiocentric T-cell lymphoma (also known as extranodal NK/T-cell lymphoma, nasal type) (8.5%), and 1 of subcutaneous panniculitis-like T-cell lymphoma (2.1%). This evidence concerns the gene TNFRSF8 and Sezary syndrome.