AIM2 and Cognitive impairment: Therefore, the ipsilesional cortical application of the classified PBM device at a certain wavelength (i.e., 630 nm) prevented tissue and functional damage in the acute ischemic brain and obviously attenuated the development of cognitive impairment in poststroke chronic phase through the combinatorial regulation of AIM2 inflammasome‐mediated pyroptosis and microglia polarization.