SIRT1 and hypopharynx cancer: A recent study showed that Ad‐ING4‐P53 and cisplatin gene therapy in hypopharyngeal cancer is associated with apoptosis induction.21, 22 ING4 regulates the p65 subunit of nuclear factor (NF)‐кB via interaction with Sirtuin1 (SIRT1) and alleviates lipopolysaccharide‐induced inflammation.23