Finally, survival analysis, biological function analysis, and literature researched identified 8 key biomarkers (lncRNA LINC01082, miRNA hsa-miR-133a-3p, mRNA TTLL12, PTGDS, GAS6, CYP27A1, PKP3, and ZG16B) to predict prostate cancer prognosis (Figure 4). Here, PKP3 is linked to Familial prostate cancer.