Western blot (Figure 5) showed that the expression levels of NF-κBp65 and IKKβ were increased, and the protein expression of IκBα was decreased in the pericentral hematoma tissues of ICH rats compared with the sham group; by comparison, the expression levels of NF-κBp65 and IKKβ were decreased and the protein expression of IκBα was increased in the tissues of the sh-H19 group compared with the sh-NC group. This evidence concerns the gene IKBKB and hematoma.