We next tested the antiproliferative effects of TH-Z835 in other non-G12D mutant cancer cell lines, including 4T1 (KRAS(WT)), MIA PaCa-2 (KRAS(G12C)), CFPAC-1 (KRAS(G12V)), and HCT116 (KRAS(G13D)) cells. This evidence concerns the gene KRAS and cancer.