Systemic values of IL-1β (p = 0.001), IL-6 (p = 0.001), IL-10 (p = 0.026), IL-23 (p = 0.001), IL-33 (p = 0.001), and Gal-1 (p = 0.001) were significantly higher in COVID-19 patients in stage III compared to patients in stage I and II (Fig. 1). The gene discussed is IL1B; the disease is COVID-19.