In addition, these results demonstrate not only increased MCT expression in high-grade tumours, but also a relative redistribution of MCT4 expression from the stromal to the epithelial compartment, as seen in both Fig. 3d and Fig. 4c, which could be used as an early biomarker of an increase in tumour epithelial glycolytic flux. The gene discussed is SLC16A3; the disease is neoplasm.