We compared this novel metabolic imaging to standard-of-care measures of tumour aggressiveness, immunohistochemical (IHC) expression of the transporters for pyruvate and lactate (MCT1 and MCT4), and mRNA expression of the enzyme subunits catalysing the exchange between the two metabolites (LDHA and LDHB). The gene discussed is SLC16A3; the disease is neoplasm.