To investigate whether GRP78 participated in the EMT process, we determined the expression of EMT markers (E-cad, N-cad and vimentin) as well as EMT transcript factors (EMT-TFs) (Snail1, Snail2, Twist, ZEB1 and ZEB2) in BPH-1 cells. This evidence concerns the gene ZEB1 and benign prostatic hyperplasia.