A relatively weak intensity of RPS27a (Fig. 8D, E), Ki-67 (Fig. 8F, G) and MMP-9 (Fig. 8H, I) staining was observed with RPS27a knockdown of xenograft tumor tissue, and a strong intensity of E-cadherin (Fig. 8J, K), p53 (Fig. 8L, M), MDM2 (Fig. 8N, O) and RPL11 (Fig. 8P, Q) was observed with RPS27a knockdown of xenograft tumor tissue. Here, RPL11 is linked to neoplasm.