Regarding individual outcomes, only stroke showed a significant interaction between AT and NAT subjects (HR = 1.43; 95% CI 1.24–1.65 for Q4 vs Q1 in AT and HR = 1.11; CI 0.96- 1.29 for Q4 vs Q1 in NAT; p for interaction 0.001) (Fig. 3). This evidence concerns the gene BRD2 and stroke disorder.