Higher CCT7 expression was also associated with greater vascular invasion (P = 0.015), higher Tumor-Node-Metastasis (TNM) staging (P = 0.049), higher tumor grading (P = 0.007), greater serum AFP levels (P < 0.001), familial cancer history (P = 0.011), adjacent hepatic inflammation (P = 0.027), fibrosis (P = 0.002), recurrence (P = 0.037) and poorer survival (P = 0.038), but was not associated with age, gender, radiation or pharmaceutical treatment (Table 1). This evidence concerns the gene AFP and hereditary cancer.