NOS3 and myocardial ischemia: The chemical compound resveratrol (RSV, 3, 5, 4-trihydroxystilbene), a naturally polyphenolic phytoalexin, has been shown to attenuate myocardial ischemia/reperfusion injury mediated via up-regulation of vascular endothelial growth factor B (VEGF-B)/AMPK/eNOS/NO signaling mechanisms in isolated rat heart preparations [212].